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Pharm. Godfrey Sambayi is a pharmacist, academician, researcher, and consultant at the Pharmacognosy Department, School of Pharmacy, MUHAS, Tanzania, dedicated to enhancing pharmaceutical research, education, and skills development. He obtained a Bachelor of Pharmacy (BPharm) in 2017 and a Master of Pharmacy (MPharm) in Pharmacognosy in 2020, both from MUHAS. His master's thesis focused on discovering natural product-derived treatments for diabetes mellitus. He subsequently pursued a PhD in Pharmaceutical Sciences at the University of Antwerp, Belgium (2022-2026), focusing on research that integrates traditional medicinal knowledge with modern analytical technologies to identify bioactive compounds from Tanzanian medicinal plants.
His PhD research, titled "Ethnopharmacological, Phytochemical, Anti-sickling, Anti-plasmodial, and Anti-HIV Investigations on Tanzanian Medicinal Plants," centers on identifying and characterizing compounds from plants that may have therapeutic uses for sickle cell disease, malaria, and HIV. His research combines bioassay-guided isolation, chromatographic separation, and advanced spectroscopic and metabolomic methods, including UPLC-ESI-QTOF-MS/MS, LC-MS-based metabolomics, 1D and 2D Nuclear Magnetic Resonance (NMR) spectroscopy, and molecular networking, to expedite the discovery of biologically active natural compounds.
Sambayi's areas of research interest span natural product chemistry, ethnopharmacology, metabolomics, phytochemical characterization, drug discovery, pharmaceutical analysis, formulation and standardization of herbal products and nutraceuticals and the application of natural products in addressing major public health challenges, particularly non-communicable and infectious diseases.
Experienced in the extraction, isolation, purification, and structural elucidation of natural products using chromatographic and spectroscopic techniques including UPLC-ESI-QTOF-MS/MS and 1D/2D NMR. Skilled in bioassay-guided fractionation and in vitro evaluation of antiplasmodial, anti-HIV, and antisickling activities.
Peer Support Groups as an Intervention to Poor Adherence to Medications among HIV patients co- infected with TB: A case study of DUCs-cohort, Dar es Salaam. Funded by MUHAS Infectious Disease Initiative (MIDI).
Completed in 2023.
Role: Principal Investigator
Sambayi G, Mwakalukwa R, Ngassapa OD, Pieters L, Tuenter M. (2026). Ethnopharmacological survey of medicinal plants traditionally used to manage sickle cell disease in Mwanza and Mara Regions, Tanzania. Sci Afr 2026; 31: e03291. doi:10.1016/j.sciaf.2026.e03291
Sambayi, G. L., Bwire, G. M., Kilapilo, M. S., Myemba, D. T., Mosha, I. H., Kilonzi, M., … Killewo, J. (2026). Impact of HIV-related stigma on quality of life among people with HIV: evidence from Dar es Salaam, Tanzania. AIDS Care, 38(2), 336–346. https://doi.org/10.1080/09540121.2025.2581203
Costantine, J.K., Mwakalukwa, R., Runyoro, D.K., Sambayi, G.L., Justine, C., & Lugoba, M. (2024). Ethnopharmacological survey of medicinal plants used by the Nyambo and Haya people of Kyerwa district in Northwestern Tanzania to treat urinary tract infections. Clinical Traditional Medicine and Pharmacology 2024; 5: 200177. doi:10.1016/j.ctmp.2024.200177
Kibwana, U.O., Maganda, B.A., Mikomangwa, W.P., Sambayi G.L., et al. Multi-layered factors contribute to irrational use of antibiotics among pediatric patients in Tanzania: ADDO dispensers’ perspective. Discov Soc Sci Health 4, 53 (2024). https://doi.org/10.1007/s44155-024-00113-0
Sambayi GL, Bwire GM, Kilapilo MS, Myemba DT, Mosha IH, Kilonzi M, Magati RB, Amour M, Mwakalukwa R, Mangara AN, Bakari M, Sudfeld CR, Matee MIN, Sangeda RZ, Adams LV, Killewo J. “Barriers and enablers to retention in HIV care and adherence to antiretroviral therapy: Evidence from Dar es Salaam, Tanzania”(2024): HIV/AIDS - Research and Palliative Care 2024, 16:301-311.
